Projects
Projects P01, P02, P03
Research Area 1: MHC-I-mediated recognition of CMV by T cells and NK cells
P01 |
Integrative analyses of CMV translatomes and MHC-I ligandomes |
Prof. Dr. Lars Dölken Prof. Dr. Florian Erhard |
Virology and Immunobiology, University of Würzburg |
P02 |
Solving the m04 paradox: Evasion of missing-self recognition and CD8 T cell killing by MAT uORF |
Dr. Vanda Juranic Lisnic Prof. Dr. Stipan Jonjic, PhD |
University of Rijeka (Croatia) |
P03 |
HCMV manipulation of antigen presentation by HLA-E by US10 | Dr. Anne Halenius | University of Freiburg |
Projects P04, P05, P06
Research Area 2: Mechanisms defining T cell / NK cell activation and function
P04 | Impact of HCMV infection on professional antigen presenting cells |
Prof. Dr. Britta Eiz-Vesper Prof. Dr. Ulrich Kalinke |
Hannover Medical School Twincore Hannover |
P05 | Role of NFAT signaling in memory inflation and T cell-mediated immune protection against CMV |
Prof. Dr. Luka Cicin-Sain PD. Dr. Friederike Berberich-Siebelt |
HZI Braunschweig University of Würzburg |
P06 | Optimizing immune cell-based protection against CMV in preclinical models | Prof. Dr. Reinhold Förster | Hannover Medical School |
Projects P07, P08, P09
Research Area 3: Improving immunological control of CMV for clinical interventions
P07 | Development of an HCMV vaccine utilizing knowledge of viral immunomodulatory functions | Prof. Dr. Martin Messerle | Hannover Medical School |
P08 | Impact of HCMV-encoded FcγR antagonists on innate immune cell function | Prof. Dr. Hartmut Hengel | University Hospital Freiburg |
P09 | Personalized medicine - Risk stratification and prevention of HCMV-related disease in transplant patients based on MHC-I-bound peptidome analysis |
Prof. Dr. Hermann Einsele Dr. Sabrina Kraus |
University Hospital Würzburg University Hospital Würzburg |