Deutsch Intern
Institute for Virology and Immunobiology

Selected publications

Selected publications:

1) Jessen, B., Faller, S., Krempl, C. D., and Ehl, S. (2011). MHC-dependent CTL repertoire and functional avidity contribute to strain-specific disease susceptibility after murine RSV infection. J. Virol. 85: 10135-10143.

2) Heinze, B., Frey, S., Mordstein, M., Schmitt-Gräff, A., Ehl, S., Buchholz, U.J., Collins, P. L., Staeheli, P., and Krempl, C. D. (2011). Both nonstructural proteins NS1 and NS2 of pneumonia virus of mice are inhibitors of the interferon type I and type III responses in vivo. J.Virol. 85:4071-4084.

3) Wilhelm, K., Ganesan, J. Müller, T., Dürr, C., Grimm, M., Beilhack, A., Krempl, C. D., Sorichter, S., Gerlach, U. V., Jüttner, E., Zerweck, A., Gärtner, F., Pellegatti, P., Di Virgilio, F., Ferrari, D., Kambham, N., Fisch, P., Finke, J., Idzko, M., and Zeiser, R. (2010). Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R. Nat. Med. 16:1434-1438.

4) Buchholz, U. J., Ward, J. M., Lamirande, E. W., Heinze, B., Krempl, C. D., and Collins, P. L. (2009). Deletion of nonstructural proteins NS1 and NS2 from pneumonia virus of mice attenuates viral replication and reduces pulmonary cytokine expression and disease. J. Virol. 83: 1969-1980.

5) Frey, S., Krempl, C. D., Schmitt-Graff, A., and Ehl, S. (2008). Role of T cells in virus control and di-sease after infection with pneumonia virus of mice. J. Virol. 82: 11619-11627.

6) Vallbracht, S., Jessen, B., Mrusek, S., Enders, A., Collins, P. L., Ehl, S. and Krempl, C. D. (2007). Influence of a single viral epitope on T cell response and disease after infection of mice with respi-ratory syncytial virus. J. Immunol. 179: 8264 - 8273.

7) Krempl, C. D., Wnekowicz, A., Lamirande, E. W., Nayebagha, G., Collins, P. L., and Buchholz, U. J. (2007). Identification of a novel virulence factor in recombinant pneumonia virus of mice. J. Virol. 81, 9490-9501.

8) Krempl, C. D., Lamirande, E. W., and Collins, P. L. (2005). Complete sequence of the RNA genome of pneumonia virus of mice (PVM). Virus Genes 30, 237-249.

9) Krempl, C. D., and Collins, P.L. (2004). Reevaluation of the virulence of prototypic strain 15 of pneumonia virus of mice. J. Virol. 78:13362-13365.

10) Krempl, C., Murphy, B.R., and Collins, P.L. (2002). Recombinant respiratory syncytial virus with the G and F genes shifted to the promoter-proximal positions. J.Virol. 76.: 11931-11942."